Recent Publications/Abstracts on Lipid Elasticity

Rajammorthi, K., H. I. Petrache, T. J. McIntosh, and M. F. Brown. Packing and viscoelasticity of polyunsaturated w-3 and w-6 lipid bilayers as seen by 2H NMR and X-ray diffraction. J. Am. Chem. Soc ., in press.

H. I. Petrache, D. Harries, V. A. Parsegian . Alteration of lipid membrane elasticity by cholesterol and its metabolic precursors , Macromolecular Symposia , 2004, in press) [pdf]

D. Harries, A. Ben-Shaul, I. Szleifer, Enveloping of charged proteins by lipid bilayers, J. Phys. Chem. B 108, 1491-1496 (2004). [pdf]

Sachs, J. N., H. I. Petrache and T. B. Woolf. Interpretation of small angle X-ray measurements guided by molecular dynamics simulations of lipid bilayers. Chem. Phys. Lipids 2004, 126:211--223. [pdf]

Teague WE, Petrache HI, Fuller N, et al., Membrane curvature elasticity of polyunsaturated phosphatidylethanolamine monolayers, BIOPHYS J 86 (1): 198A-198A Part 2 Suppl. S JAN 2004

Martinez GV, Dykstra EM, Lope-Piedrafita S, et al.,  Lanosterol and cholesterol-induced variations in bilayer elasticity studied by deuterium NMR and X-ray diffraction. BIOPHYS J 86 (1): 200A-200A Part 2 Suppl. S JAN 2004

D. Harries, S. May and A. Ben-Shaul "Curvature and charge modulations in lamellar DNA-lipid complexes" J. Phys. Chem. B 107, 3624-3630 (2003). [pdf]

R. Podgornik, D. Harries, H.H. Strey, V.A. Parsegian. "Molecular interactions in lipids, DNA, and Lipid-DNA complexes" in "Gene Therapy - therapeutic mechanisms and strategies", N. Smyth Templeton edt., 2nd ed. (2003). [pdf]

Petrache HI, Thurmond RL, Brown MF, Material properties of DOPE/DOPC mixtures measured by POPC-d31 probesin solid-state 2H NMR, BIOPHYS J 84 (2): 375A-375A Part 2 Suppl. S FEB 2003

Petrache HI, Brown MF, Universal features of acyl chain packing in fluid lipid bilayers, BIOPHYS J 82 (1): 741 Part 2 JAN 2002

Petrache, H. I., D. M. Zuckerman, J. N. Sachs, J. A. Killian, R. E. Koeppe II, and T. B. Woolf. Hydrophobic Matching Mechanism Investigated by Molecular Dynamics Simulations. Langmuir 2002, 18:1340--1351. [pdf]

Petrache, H. I., A. Salmon, and M. F. Brown. Structural Properties of Docosahexaenoyl Phospholipid Bilayers Investigated by Solid-state 2 H NMR Spectroscopy. J. Am. Chem. Soc. 2001, 123:12611--12622. [pdf]

Related Publications

Petrache, H. I., S. W. Dodd, and M. F. Brown. Area per Lipid and Acyl Length Distributions in Fluid Phosphatidylcholines Determined by 2 H NMR Spectroscopy. Biophys. J. 2000, 79:3172-3192. [pdf]

Petrache, H. I., K. Tu, and J. F. Nagle. Analysis of Simulated NMR Order Parameters for Lipid Bilayer Structure Determination. Biophys. J. 1999, 76:2479-2487. [pdf]

Petrache, H. I., S. Tristram-Nagle, and J. F. Nagle. Fluid Phase Structure of EPC and DMPC Bilayers. Chem. Phys. Lipids 1998, 95:83-94. [pdf]

Petrache, H. I., S. E. Feller, and J. F. Nagle. Determination of Component Volumes of Lipid Bilayers from Simulations. Biophys. J. 1997, 72:2237--2242. [pdf]

Petrache, H. I., A. Grossfield, K. R. MacKenzie, D. M. Engelman, and T. B. Woolf. Modulation of Glycophorin A Transmembrane Helix Interactions by Lipid Bilayers -- Molecular Dynamics Calculations. J. Mol. Biol. 2000, 302:727--746. [pdf]

S. May, D. Harries and A. Ben-Shaul "Macroion-induced compositional instability of binary fluid membranes" Phys. Rev. Lett. 89 , art. no. 268102 (2002). [pdf]

D. Harries "Electrostatic interactions between macromolecules and lipid bilayers" Ph.D. Thesis, Hebrew University (2001). [pdf]

S. May, D. Harries and A. Ben-Shaul "The Phase Behavior of Cationic Lipid-DNA Complexes" Biophys. J. 78, 1681-1697 (2000). [pdf]

D. Harries, S. May, W. M. Gelbart and A. Ben-Shaul "Structure, Stability and Thermodynamics of Lamellar DNA-Lipid Complexes" Biophys. J. 75, 159-173 (1998). [pdf]

D. Harries and A. Ben-Shaul "Conformational Chain Statistics in a Model Lipid Bilayer: Comparison Between Mean Field and Monte Carlo Calculations" J. Chem. Phys. 106 , 1609-1619 (1997). [pdf]

S. May, D. Harries and A. Ben-Shaul "Lipid Demixing and Protein-Protein Interactions in the Adsorption of Charged Proteins on Mixed Membranes" Biophys. J. 79, 1747-1760 (2000). [pdf]

Nagle, J. F., R. Zhang, S. Tristram-Nagle, W.-J. Sun, H. I. Petrache, and R. M. Suter. X-Ray Structure Determination of Fully Hydrated L_\alpha Phase Dipalmitoylphosphatidylcholine Bilayers. Biophys. J. 1996, 70:1419--1431.

Parsegian, V.A.: A theory on the stability of liquid crystalline phases of lipid-water system.  Thesis.  Harvard, 1965.

Parsegian, V.A.: Theory of Liquid-Crystal Phase Transitions in Lipid and Water Systems.  Trans. Faraday Soc. 62: 848, 1966.

Parsegian, V.A., Fuller, N., Rand, R.P.: Measured work of deformation and repulsion of lecithin bilayers.  PNAS 76: 2750-2754, 1979. [pdf]

Parsegian, V.A., Gingell, D.: Red blood cell adhesion III analysis of forces. J. Cell Science 41: 151-157, 1980.

Rand, R.P., Parsegian, V.A., Henry, J.A.C., Lis, L.J., McAlister, M.: The effect of cholesterol on measured interaction and compressibility of dipalmitoylphosphatidylcholine bilayers.  Canad. J. Bioch. 58: 959-968, 1980.

Parsegian, V.A., Rand, R.P., Stamatoff, J.: Perturbation of membrane structure by uranyl acetate labelling.  Biophys. J. 33: 475-478, 1981.

Lis, L.J., McAlister, M., Fuller, N., Rand, R.P., Parsegian, V. A.: Measurement of the lateral compressibility of several phospholipid bilayers.  Biophys. J. 37: 667-672, 1982.

Gruen, D.W.R., Marcelja, S., Parsegian, V.A.: Water structure near the membrane surface.  In Cell Surface Dynamics.  Marcel Dekker, Inc., New York, pp.59-91, 1984.

Rau, D.C., Lee, B., Parsegian, V.A.: Measurement of the repulsive force between polyelectrolyte molecules in ionic solution:  Hydration forces between parallel DNA double helices.  PNAS 81: 2621-2625, 1984.

Parsegian, V.A., Rau, D.C.: Water near intracellular surfaces.  J. Cell. Biol. 99: 196-200, 1984.

Rand, R.P., Parsegian, V.A.: Physical force considerations in model and biological membranes.  Can. J. Biochem. Cell Biol. 62: 752-759, 1984.

Parsegian, V.A., Rand, R.P. Rau, D.C.: Hydration forces:  What next?  In: Hydration forces and molecular aspects of solvation.  B. Jonsson, H. Wennerstrom and S. Forsen, eds.  Chemica Scripta 25: 28-31, 1985.

Rand, R. P., Parsegian, V.A.: Mimicry and mechanism in phospholipid models of membrane fusion.  Ann. Revs. Physiol., 48: 201-212, 1986.

Evans, E.A., Parsegian, V.A.: Thermal-mechanical fluctuations enhance repulsion between biomolecular layers.  PNAS 183: 7132-7136, 1986. 

Parsegian, V.A., Rau, D.C., Zimmerberg, J.: Structural transitions induced by osmotic stress in anhydrous biological systems.  Chapter 18 pp.306-317 in Leopold, A.C. (Ed.): Membranes, Metabolism, and Dry Organisms.  Cornell University Press, Ithaca, NY, 1986.

Zimmerberg, J., Parsegian, V.A.: Polymer inaccessible volume changes during opening and closing of a voltage dependent ionic channel.  Nature (London), 323: 36-39, 1986.

Gruner, S.M.,Parsegian, V.A., Rand, R.P.: Directly measured deformation energy of phospholipid H11 hexagonal phases.  Faraday Discuss. Chem. Soc. 81: 29-37, 1986.

Rand, R.P., Parsegian, V.A.: The influence of polar group identity on the interactions between phospholipid bilayers.  In S. Ohki, D. Doyle, T.D. Flanagan, S.W. Hui, E. Mayhew (Eds.).: Molecular Mechanism of Membrane Fusion, pp.73-81, 1988.

Rand, R.P., Fuller, N.L., Gruner, S.M., Parsegian, V.A.: Membrane curvature, lipid segregation and structural transitions for phospholipids under dual solvent stress.  Biochem. J. 29: 76-87, 1990.

Zimmerberg, J., Bezanilla, F., Parsegian, V.A.: Solute inaccessible aqueous volume changes during opening of the potassium channel of the squid giant axon.  Biophys. J. 57: 1049-1064, 1990.

Parsegian, V.A., Rand, R.P.: Forces Governing Lipid Interaction and Rearrangement.  In J. Wilschut, D. Hoekstra (Eds.): Cellular Membrane Fusion.  Marcel Dekker, New York, 1990.

Podgornik, R., Parsegian, V.A.: Molecular fluctuations in packing of polymeric liquid crystals.  Macromolecules 23: 2265-2269, 1990. 

Gawrisch, K., Parsegian, V.A., Rand, R.P.: Membrane hydration.  In R. Glaser, D. Gingell (Eds.).: Biophysics of Cell Surfaces.  Springer-Verlag, New York, 1990.

Rau, D.C., Parsegian, V.A.: Direct measurement of the intermolecular forces between counterion- condensed DNA double helices: Evidence for long-range attractive hydration forces.  Biophys. J. 61: 246-259, 1992. 

Podgornik, R., Parsegian, V.A.: Thermal-mechanical fluctuations of fluid membranes in confined geometries: The case of soft confinement.  Langmuir 8: 557-562, 1992. 

Gawrisch, K., Ruston, D., Zimmerberg, J., Parsegian, V.A., Rand, R.P., Fuller, N.: Membrane dipole potentials, hydration forces, and the ordering of water a membrane surfaces.  Biophys. J. 61:1213-1223, 1992. 

Gawrisch, K., Parsegian, V.A., Hajduk, D.A., Tate, M.W., Gruner, S.M., Fuller, N.L., Rand, R.P.: Energetics of a hexagonal-lamellar-hexagonal phase transition sequence in dioleoylphosphatidyl-ethanolamine membranes.  Biochem. J. 31: 2856-2864, 1992. 

Tsao Y, Evans F, Rand RP, Parsegian VA.  Osmotic stress measurements of dihexadecldimethylammonium acetate bilayers as a function of temperature and added salt.  Langmuir, 9: 233-241, 1993.

Keller SL, Bezrukov SM, Gruner SM, Tae MW, Vodyanoy I, Parsegian VA. Probability of alamethicin conductance states varies with nonlamellar tendency of bilayer phospholipids.  Biophysical Journal, 65:23-27, 1993.

Parsegian VA.  The cows or the fence.  Molecular Membrane Biology, 12:5-7,1995.

Rand RP, Parsegian VA.  Hydration, Curvature, and Bending Elasticity of Phospholipid Bilayers.  In:  Lipid  polymorphism and Membrane Properties,  Epand R, ed., Current topics in Membranes, Vol. 44, Academic Press.

Parsegian, VA.  Harness the Hubris: useful things physicists might do in biology.  Physics Today, 1997;23-27.

Bezrukov SM, Rand PR, Vodyanoy I, Parsegian VA.  Lipid packing stress and polypeptide aggregation: alamethicin channel probed by proton titration of lipid charge, Faraday Discussion 1999, III:173-183.

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